The Important Nutritional Compound Glutathione

By Tracy Done


Glutathione is a substance produced by the liver which has many beneficial effects on the body. It is not a true amino acid (amino acids are chemicals that make up protein in our systems and that are released by the metabolism of animal protein that we eat) but is a product of the synthesis of three of these important nutrients. Produced by the liver, glutathione works as a detoxifier and an antioxidant.

The supplies of this substance in the body are found mainly in the liver, where it aids in that organ's detoxifying functions. However, it is also present in the bloodstream, where it appears to help break down oxidized fats. These fats can clog arteries and have other detrimental effects on tissues and organs. In the intestines, glutathione aids in carbohydrate digestion. Throughout the body, it destroys harmful free radicals that accelerate the aging process and contribute to disease and chronic conditions.

Although all of us need this important nutrient, those who smoke or drink excessive amounts of alcohol will benefit the most. Glutathione appears to protect the lungs from harmful chemicals in tobacco smoke. It also seems to protect liver cells from damage by alcohol.

A deficiency of this substance is demonstrated most clearly in the nervous system. People lacking in glutathione suffer loss of coordination and balance, develop tremors, and exhibit mental disorders. The effects of aging also are accelerated throughout the body.

As with many other important chemicals in the body, the levels of glutathione decrease with age. It may be that less is produced by the liver or that more is used to combat the effects of aging. Its action in protecting the mind and the body makes some health practitioners call glutathione the 'master antioxidant.' As research into the intricate workings of our metabolism proceed, more and more is learned about the activities of this and other vital chemicals.

It comes as a single substance in capsules, and is also available in combination formulas. However, since the compound is not found in food but is produced internally by our own bodies, the value of oral supplements is questioned by some health experts. It may be that supplementation of the three amino acids that are used to produce Glutathione is a better way to get an adequate supply.

The three amino acids that the body uses to produce glutathione are cysteine, glutamic acid, and glycine. Most of the building blocks of protein are found in food, but they can be destroyed by cooking. Supplements of the nutrients are helpful, but care must be taken to ingest the right amounts. Too much of a good thing can actually be harmful and can cause imbalances in the delicate mechanisms of our metabolism.

Because keeping the right balance of nutrients is important, care should be taken when deciding how and when to supplement glutathione. It is best to proceed with the advice of a trained practitioner or by relying on a formula prepared by a manufacturer which bases its products on clinical testing. There is a lot of information on amino acid therapies, and many sources are peer-reviewed to be reliable. Anyone with health issues that indicate a higher need for this compound should invest the time and energy to learn how to use it to best advantage.




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